This article uncovers the rise of anti-intellectualism and populism in American politics and how this worldview has been reflected in the Trump administration. It mentions the appointment of Robert Kennedy, Jr., with his skepticism towards vaccines, which openly challenges scientific consensus. The article points out that Trump and Kennedy both hold anti-intellectual and populist views, pitting ordinary citizens against so-called elites while denigrating scientific experts. This sentiment has been widely echoed among Americans, partly due to public discontent with the elite class and dissatisfaction with health, drug, and public health policies. However, the rise of anti-intellectualism may lead to a crisis of trust in science and medicine, potentially triggering a real public health crisis.